Week 5 SEC Picks and College Football Best Bets

TUSCALOOSA, ALABAMA - SEPTEMBER 23: Head coach Nick Saban of the Alabama Crimson Tide reacts after their 24-10 win over head coach Lane Kiffin of the Mississippi Rebels at Bryant-Denny Stadium on September 23, 2023 in Tuscaloosa, Alabama. (Photo by Kevin C. Cox/Getty Images)
TUSCALOOSA, ALABAMA - SEPTEMBER 23: Head coach Nick Saban of the Alabama Crimson Tide reacts after their 24-10 win over head coach Lane Kiffin of the Mississippi Rebels at Bryant-Denny Stadium on September 23, 2023 in Tuscaloosa, Alabama. (Photo by Kevin C. Cox/Getty Images) /
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The Vanderbilt Commodores mascot Mr. Commodore
LAS VEGAS, NEVADA – SEPTEMBER 16: The Vanderbilt Commodores mascot Mr. Commodore poses in the third quarter of the team’s game against the UNLV Rebels at Allegiant Stadium on September 16, 2023 in Las Vegas, Nevada. The Rebels defeated the Commodores 40-37. (Photo by Ethan Miller/Getty Images) /

No. 23 Missouri (-13) @ Vanderbilt – O/U 54.5

Evan Ertel: It’s not rocket science. Vanderbilt is terrible, Missouri may finish second in the East. Don’t overthink it, just hammer the Tigers. Missouri -13

Ryan Strickland: Vanderbilt is just a really bad football team. They are also 0-5 ATS this season. Missouri has gained a lot of momentum over the past few weeks and it will continue against Vandy. Missouri -13

Justin Strawn: Vandy continues to be bad, and Missouri continues to be surprisingly good. Missouri -13

Ethan Lee: Missouri has been weird and up and down, but the Tigers keep winning. The Commodores aren’t. I’m trusting the Tigers to win big in this one. Missouri -13

Andrew Miller: What would’ve been a popular upset pick before the year no longer seems like it’ll be much of a game. Mizzou plays weird games, but Vandy just isn’t good. Missouri -13

John King: Mizzou comes into this game 4-0, but their average margin of victory against FBS opponents is 4.7 (including a 4-point victory over MTSU). I like the Tigers’ chances of winning this one, but 13 seems like too large of a margin. Vandy +13